New strategy of homology-independent targeted integration published in Nature

Date: 2018-09-06
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In Dec. 2016, the Nature journal published a new strategy for gene editing (homology independent targeted integration, HITI), which developed by the team of Juan Izpisua Belmonte in the Salk Institute. Their study proved that HITI can be used for gene editing in vitro and in vivo efficiently, and may be very important for basic research and targeted gene therapy in future!

 

Suzuki, K. et al. In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration. Nature 540, 144-149 (2016).


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